ITGAM and cancer: Compounds C.3 (p-fluorophenyl urea) and C.12 (p-methoxyphenyl urea) were the most promising agents for several reasons: they inhibited 50% of both biological targets; they were the most effective as antiangiogenic agents: they reduced to the half the cancer cell viability in the presence of monocytes and reduced CD11b expression on monocytes without causing any damage on them.