Recently, a new SPECT tracer [99mTc]Tc-HYNIC-D-Ala-boroPro ([99mTc]Tc-iFAP, Figure 1) targeting FAP was reported to exhibit 7.05 ± 1.13 %ID/g tumor uptake and 11.18 ± 1.54 %ID/g kidney uptake in an induced Hep-G2 tumor model in mice at 30 min post injection (pi) [23]. Here, MBTPS2 is linked to neoplasm.