In recent years, studies based on Mendelian randomisation approaches questioned this effect, consisting of analyses from a genetic approach where it was observed that a reduced risk of coronary heart disease among carriers of the alcohol dehydrogenase 1B (ADH1B) gene was evident when they drank less alcohol, concluding that reducing alcohol consumption is beneficial for cardiovascular health [17]. The gene discussed is ADH1B; the disease is coronary artery disorder.