MTOR and type 2 diabetes mellitus: It was shown in animal models that a combination of quercetin and metformin—a drug belonging to the biguanide group, commonly used as an oral antidiabetic drug for the treatment of type 2 diabetes—had a positive effect on the size of endometrial implants, as well as the expression levels of mammalian target of rapamycin (mTOR) and autophagy marker genes in the ectopic endometrium [78].