KL and renal fibrosis: Our findings suggest an anti-aging mechanism underlying the relationship between a healthy diet and enhanced kidney function through the involvement of serum α-Klotho, which plays a crucial role in preserving kidney health by regulating calcium and phosphate metabolisms, inhibiting renal fibrosis, reducing oxidative stress, and promoting anti-inflammatory effects [7,8,9,10,11,12,13,14,15].