OXCT1 and neoplasm: Zhang et al. showed that the utilization of ketone bodies for tumor growth requires the presence of four ketolytic enzymes, namely D-beta hydroxybutyrate dehydrogenases 1 and 2 (BDH1 and BDH2) and 3-oxoacid CoA transferases 1 and 2 (OXCT1 and OXCT2) [19].