CDX2 and colorectal carcinoma: Although tests for interaction between VitD status and Cdx2 genotype with respect to survival did not reach statistical significance in our cohort, the pattern of strong inverse associations between VitD and mortality among those with the GG genotype, and absence of these associations among those with the AA/AG genotype is highly consistent with observations from two somewhat smaller CRC patient cohorts from the UK (n = 1687 and n = 1848, respectively) [7].