However, Jensen et al. [37] showed that, in a randomized, double-blind study with adults suffering from metabolic syndrome (n = 15, mean age of 53 years old), the supplementation with 4 g of cod peptides over eight weeks had an impact on the levels of high-sensitivity C-reactive protein, whereas the other parameters evaluated (e.g., fasting and postprandial levels of acylated ghrelin, and fasting levels of adiponectin, leptin) did not show any statistically significant differences. The gene discussed is LEP; the disease is metabolic syndrome.