Neutrophils contribute to the development of lung cavities [18,30], and we therefore assessed the correlation of the neutrophils and the concentrations of the plasma biomarkers MMP-1, MMP-2, MMP-8, MP0 and S100A8 at BL, month 6 (end of TB treatment) and month 12 (6 months post TB treatment). This evidence concerns the gene S100A8 and tuberculosis.