AR and Familial prostate cancer: QW07 (4) has IC50 values of 0.50 μM and 0.54 μM towards the PC-3 and DU145 cell lines using SRB cell proliferation assay after 96 h of treatment [16], implying QW07 (4) can suppress both AR-positive and AR-negative prostate cancer cell proliferation through AR-dependent and AR-independent pathway.