DGAT1 and viral infectious disease: Quercetin decreased the production of reactive oxygen and nitrogen species (ROS/RNS) and lipid peroxidation induced by HCV and inhibited HCV replication. Quercetin decreased the increased expression of diglyceride acyltransferase 1 (DGAT1) mRNA after viral infection and inhibited HCV genome replication.Quercetin can affect the morphogenesis of infectious particles and reduce HCV-specific infectivity. The integrity of virions is affected when applied directly to HCV particles, hindering the localization of the HCV core protein in LDs.