Nearly 60% of melanomas show BRAF mutations [18], and mutations in this gene are also found in non-Hodgkin’s lymphoma [19], CRC [20,21], thyroid papillary carcinoma [22,23], non-small-cell lung cancer [24,25,26], glioblastoma [27], and inflammatory diseases [28,29]. The gene discussed is BRAF; the disease is colorectal carcinoma.