Given the pathological processes that characterize PTSD, there are also some therapies that can alleviate the severity of the condition: metformin, thiazolidinediones, PPAR agonists, angiotensin receptor type I blockers, angiotensin converting enzyme inhibitors, cannabinoid receptor antagonists (upregulation of adiponectin), quercetin, coenzyme Q10, and resveratrol (improvement of mitochondrial dysfunction) [136]. This evidence concerns the gene ADIPOQ and post-traumatic stress disorder.