In the study by Nakkaş et al., the expressions of UPS proteins such as p97/VCP, ubiquitin and Jab1/CSN5 and autophagic proteins such as p62, LC3B and Beclin1 were analyzed with the immunohistochemical method in 120 cases of testicular cancer from orchiectomy materials. This evidence concerns the gene COPS5 and testicular cancer.