RAN and hepatocellular carcinoma: The RAN*rs14035 variant showed a significant association with elevated risk of HCC compared to cancer-free controls among different hereditary models, including homozygote (OR = 2.44, 95% CI = 1.27–4.68, p-value < 0.001) and recessive (OR = 3.27, 95% CI = 1.83–5.83, p-value < 0.001) (Table 3).