Additionally, in this case, the relationship with other autoimmune diseases is apparent: in rheumatoid arthritis, it has been demonstrated that there is a very significant positive correlation between SIRT1 and autoantibodies (such as the anti-cyclic citrulline polypeptide antibody and the anti-mutant citrulline vimentin antibody) [54]. Here, SIRT1 is linked to rheumatoid arthritis.