Additionally, these specialty society guidelines recommend viral hepatitis testing (hepatitis B surface antigen and hepatitis C antibody), a serologic hemochromatosis assessment (ferritin and transferrin saturation), autoimmune hepatitis testing (anti-mitochondrial, anti-smooth-muscle, and anti-nuclear antibodies, as well as serum immunoglobulins), and imaging with an abdominal ultrasound (US) (Box 1) [43,44]. The gene discussed is TF; the disease is viral hepatitis.