Other studies have shown that elevated levels of soluble HLA-G from the bronchoalveolar lavage fluid are associated with low serum IgE [53] or that serum HLA-G expression levels, which are increased in inflammatory diseases (e.g., asthma and allergic rhinitis), are associated with increased serum levels of specific IgE [50,54,55]. This evidence concerns the gene IGHE and asthma.