IGHE and asthma: Despite the fact that the association between SNP rs549908 and total IgE in asthma or other allergic respiratory conditions has not been evaluated in Caucasians, statistically significant results were obtained in this population for polymorphisms in LD with rs549908 (rs1946519 (r2 = 0.524), rs1946518 (r2 = 0.524), rs187238 (r2 = 0.842), rs360718 (r2 = 0.842), rs360717 (r2 = 0.842), and rs360721 (r2 = 1.0); r2 was calculated for the population of Northern Europeans from Utah (CEU) using the LDlink web application (ldlink.nih.gov (accessed on 18 May 2023))) [33,34,35].