The aim of the study was to assess the relationship between the parameters of three ROTEM® tests (NATEM®, EXTEM®, and FIBTEM®) and the profile of inflammatory cytokines including CRP, interleukin-8 (IL-8), interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor (TNF), and interleukin 12p70 (IL-12p70) in non-ICU COVID-19 patients. The gene discussed is IL1B; the disease is COVID-19.