NFE2L2 and acute lymphoblastic leukemia: Nevertheless, we confirmed that NFE2L2 expression is above the mean in around 40% of T-ALL patients from two different cohorts and that it is significantly higher in patients belonging to the upper quartile (NFE2L2-Q4), suggesting that an increase in NFE2L2 transcription would be a key mechanism able to induce activation of NRF2 signalling in T-ALL.