For instance, lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α factor (LITAF, also named PIG7, a translation factor) promotes target genes (including TNF-α, IL-6, CCL-2, etc.), thereby further activating the NF-κB signal to promote a mesenchymal transition and increase the radiosensitivity of GBM [129]. The gene discussed is TNF; the disease is glioblastoma.