Phenethyl isothiocyanate (PEITC), extracted from cruciferous vegetables, significantly reduced the levels of proinflammatory cytokines, such as IL-1β, TNF-α, and IL-6, in transcriptional levels and modulated AKT- and ERK-dependent and NF-κB signaling pathways in GBM [138]. The gene discussed is MAPK1; the disease is glioblastoma.