Additionally, there are conflicting data regarding whether some ZFPs, e.g., SALL1 [185,196], ZIC5 [197,198], ZNF148 [199,200,201], and ZNF750 [202,203], are CRC tumor suppressors or oncogenes; this raises the possibility they have dual functions depending on tumor stage—additional studies are needed to explore this possibility. Here, ZIC5 is linked to neoplasm.