Supporting our findings, Nady et al. [72] observed that the in vitro formation of granulomas induced by S. mansoni soluble egg antigen (SEA) significantly decreased in the presence of IL-22 and IL-17 together, while in the presence of IL-17 alone, there is granuloma growth due to the inflammatory role of this cytokine. The gene discussed is IL22; the disease is Granuloma.