PARP1 and colorectal carcinoma: The genetic or pharmacologic manipulation of β-catenin caused an autophagy-to-apoptosis switch’ that implied the activation of caspase-3, the cleavage of PARP and the decrement of phosphorylated ERK1/2, beclin-1 and ras-related in brain 7 (Rab7) autophagy proteins levels, which in turn strikingly impacted the fate of CRC cells.