The phosphorylated FoxO3a binds to γ-aminobutyric acid receptor-associated protein-like 1 (GABARAPL-1) promoter and upregulates the transcription level of GABARAPL-1, activating an autophagic process that serves as a survival signal against apoptosis in both CRC cells and colon xenograft models [71]. The gene discussed is GABARAPL1; the disease is colorectal carcinoma.