The most important pathway involved in the induction and regulation of apoptosis and autophagy in CRC is the Wnt pathway and its component components, such as β-catenin, disheveled (Dvl), adenomatous polyposis coli (APC) and axin, that are activated along with the Wnt signaling cascade during cancer development [93]. The gene discussed is APC; the disease is colorectal carcinoma.