A study examining the relationship between long non-coding RNA cancer susceptibility candidate 2 (lncRNA CASC2) and microRNA19 (miR19) in colon cancer reported that lncRNA CASC2 suppressed expressions of LC3 and SQSTM1/p62 and significantly reduced cell viability of colon cancer cells, promoting apoptosis. The gene discussed is CASC2; the disease is malignant colon neoplasm.