Over-representation analysis shows the related GO terms for both ORF proteins in each pair: ‘GO:0016311~dephosphorylation’ and ‘GO:1903293~phosphatase complex’ (C2orf74 and C20orf27) as well as ‘PA444750~leukemia’ and ‘PA444761~ leukemia, myeloid’ (C5orf24 and C16orf71) (Table S4). The gene discussed is ADISSP; the disease is leukemia.