As it follows from Table S3, among such tissue- and cancer-specific PPIs, there are the following hits: C2orf88 and PRKAR1A (brain tissue), C5orf24 and WDR45B (thymoma), C5orf24 and GOPC (thymoma), C6orf132 and CDH1 (colon transverse), C6orf132 and EZR (colon), CXorf56 and RPRD1B (thymoma) and C16orf87 and ANAPC10 (thymoma). This evidence concerns the gene EZR and cancer.