In general, overexpression of the C4orf46, C9orf40, C17orf67 and C21orf58 gene of thymoma correlates with tumor immune cell infiltration and gene expression levels of C1orf162, C16orf54 and CXorf21 correlate with immune cell infiltration in many primary and metastatic tumors (Table S2). The gene discussed is C21orf58; the disease is thymoma.