It was shown that genes included in ‘TGCT-specific 100-gene expression signature’ have no comprehensive prognostic significance in the TGCT cohort, except for a ‘panel’ of six genes—C11orf94, C1orf105, C20orf144, C22orf31, C9orf13 and CXorf49. Here, FREY1 is linked to testicular germ cell tumor.