The studies of Zhang et al. show that the induction of apoptosis via inhibition of BCL-2 is affected by the upregulation of miR-148a in CRC, while downregulation is associated with an increase in tumor size [35], whereas reduced expression of miR-34a and miR-200c is associated with metastases in CRC [36,37]. Here, BCL2 is linked to colorectal carcinoma.