Aslam et al. report important proteins involved in key CRC signaling pathways, such as Wnt/β-catenin, phosphatidylinositol 3-kinase (PI3K), KRAS, and tumor protein 53 (p53), which are affected by miRNA expression, indicating a relationship between miRNAs and the development of colorectal cancer [42]. This evidence concerns the gene TP53 and colorectal carcinoma.