Our results showed decreased expression levels of phospho-MEK1/2(Ser217/Ser221), phospho-ERK1/2(Thr202/Thr204), phospho-p90RSK(Ser380), and the transcription factors (c-Fos and c-Myc) after treatment with ZLMP110-277, ZLMP277-110, ZLMP1-C277, and ZLMP2A-N110 in NPC-positive cell lines (Figure 7C,D). This evidence concerns the gene MAPK3 and nasopharyngeal carcinoma.