Furthermore, other in vitro and in vivo studies highlighted a selective action of G. lucidum extracts and the commercial extract ReishiMax GLpTM (carpophore and cracked spores) on mice injected with inflammatory breast cancer (IBC) on the protein expression of E-cadherin, mammalian target of rapamycin (mTOR), human eukaryotic translation initiation factor 4G (eIF4G), and p70 ribosomal protein S6 kinase (p70S6K) as well as on the activity of extracellular regulated kinase (ERK 1/2), along with the reduction in tumor size and weight [91,99,100]. This evidence concerns the gene MTOR and neoplasm.