Inhibition of cell proliferation, suppression of tumor growth in nude mice xenografts; induction of macrophages polarization towards M1 phenotype and production of Il-6, IL-1 β, TNF-α, CoX-2; induction of nitric oxide, activation of NF-κB and cell growth inhibition, probably due to the activity on macrophages; inhibition of proteins synthesis; lectins induce cytotoxicity, apoptosis, and immune system modulation [33,47,48,49,50,51]. This evidence concerns the gene TNF and neoplasm.