Similarly, while HOTAIR has been associated with poor prognosis in OC [122], it also exhibits good characteristics as a diagnostic biomarker for multiple tumors, such as diffuse large B-cell lymphoma (DLBCL) (AUC: 0.71; sensitivity, 72.6%; specificity, 69.7%) [142], glioblastoma multiforme (GBM) (area under the ROC curve: 0.913; sensitivity, 86.1%; specificity, 87.5%) [143], and esophageal squamous cell carcinoma (ESCC) (AUC: 0.793) [144]. This evidence concerns the gene HOTAIR and glioblastoma.