Some molecules induce ferroptosis through the joint action of the multiple targets above, including GPX4, SLC7A11, system Xc−, etc. Alloimperatorin induces breast cancer cell ferroptosis by reducing mRNA and protein expression levels of SLC7A11 and GPX4, which promotes the accumulation of Fe2+, ROS, and MDA, thereby inhibiting cell growth and invasion (Table 5) [114]. The gene discussed is GPX4; the disease is breast carcinoma.