Plasma NPY levels were higher in patients with adrenal pheochromocytoma than in healthy patients, or those with extra-adrenal pheochromocytoma, and tissue NPY levels were also higher in patients with adrenal pheochromocytoma than in those with extra-adrenal pheochromocytoma [222]. The gene discussed is NPY; the disease is adrenal gland pheochromocytoma.