LDHA and cancer: Moreover, apart from its relevance in cancer, human LDHA isozyme (hLDHA) has recently attracted great interest among scientists, due to its proven important role in molecular mechanism of different kind of disorders [8], such as vascular diseases [9,10], epilepsy [11,12], tuberculosis [13], pulmonary fibrosis [14], arthritis [15] and other inflammatory diseases [16,17], and in primary hyperoxalurias (PHs) [18].