NFE2L2 and cranioectodermal dysplasia: Particularly, wheat germ peptides exerted a beneficial role in an in vitro model of CeD through the activation of the Nrf2 pathway [113]; moreover, resveratrol, a well-known Nrf2 inducer, led to a reduction in oxidative stress and epithelial cell damage in in vitro and in vivo CeD models [114].