However, treatment with dexamethasone leads to a decrease in the expression of PD-L1 in other cancer cell lines, including SGC-7901 (human gastric cancer cell line), MKN-45 (human gastric cancer cell line), SMMC-7721 (human hepatocarcinoma cell line), and BxPC3 (human pancreatic cancer cell line). The gene discussed is CD274; the disease is familial pancreatic carcinoma.