NPPC and mucopolysaccharidosis: We did not see significant differences between WT and untreated MPS IVA mice, partly because of the limited number of mice (Analysis of Trabecular Bone Morphometry n = 5 in each group (Figure 6d–j); Cortical Bone Architecture WT; n = 5, MPS IVA; n = 5, AAV8-NPPC; n = 4 (Figure 6n–s).