Epithelial cell (primarily cancer cells) composition was significantly enriched in high-LPAR2 and -LPAR3-expressing tumors in all three cohorts (all p < 0.001) but decreased in high-LPAR1, -LPAR5, and -LPAR6-expressing tumors (all p < 0.05, Figure 7A). Here, LPAR5 is linked to cancer.