INS and metabolic dysfunction-associated steatohepatitis: The CC diet was developed to mimic the cholesterol-mediated insulin resistance, cardiovascular risk increase, and NASH; the CC diet produces steatosis, inflammation, HSC activation, and fibrosis; however, animals fed with this diet are not insulin-resistant; and tend to lose weight and have lower triglyceride levels, with respect to standard chow-fed mice [2].