To comprehensively evaluate the immune infiltration characteristics of two AD subgroups and one control group, we applied the CIBERSORT algorithm to estimate the proportions of 12 immune cell types (i.e., B cells, plasma cells, CD8+ T cells, CD4+ T cells, γδ T cells, NK cells, monocytes, macrophages, dendritic cells, mast cells, eosinophils, and neutrophils) in each sample. The gene discussed is CD8A; the disease is Alzheimer disease.