According to the combined tumor and normal samples from TCGA, TARGET, and GTEx, RICTOR was significantly overexpressed in GBMLGG, LGG, ESCA, STES, STAD, HNSC, WT, PAAD, ALL, LAML, PCPG, and CHOL, compared to normal tissues (Figure 1A), and significantly downregulated in GBM, UCEC, BRCA, CESC, LUAD, KIRP, COAD, COADREAD, PRAD, LUSC, SKCM, BLCA, THCA, OV, TGCT, UCS, and ACC. This evidence concerns the gene RICTOR and glioblastoma.