PD-L1 expression was detected in 20 of the 56 cases analysed, and PD-L1 expression on tumour cells was significantly increased with an increased infiltration of TIL into the tumour microenvironment; in addition, a lower TIL score corresponded to poorer prognostic clinicopathological parameters, such as a higher number of mitotic figures, Clark level and Breslow thickness. This evidence concerns the gene CD274 and neoplasm.