Kaunitz J.G. et al. [17] conducted an important study on the expression of immunohistochemistry for PD-L1 on 200 formalin-fixed paraffin-embedded (FFPE) specimens from patients with acral (n = 16), mucosal (n = 36), uveal (n = 103), and chronic sun-damaged (CSD) (n = 45) melanomas (24 lentigo maligna, 13 “mixed” desmoplastic, and 8 “pure” desmoplastic melanomas) in order to understand whether there was a differential expression of PD-L1 and CD8+ according to different MM histotypes. This evidence concerns the gene CD274 and Miyoshi myopathy.