IGF1 and familial dilated cardiomyopathy: Moreover, a study on DCM rats revealed that the intramuscular injection of human umbilical cord-derived mesenchymal stem cells (hUCMSC) improved cardiac function, and the same study suggested that the expression of IGF-1, HGF, and VEGF in the myocardium of DCM rats was remarkably increased by hUCMSC injection [83].