TP53 and lung cancer: Furthermore, various PIK3CA and/or TP53 mutations were identified together in seven out of sixteen patients with lung cancer: p.C277F of the TP53 (8.22%) in D279, p.R248L of the TP53 (3.37%) in D416, p.G154V of the TP53 (71.66%) in D045, p.E542K of the PIK3CA (8.26%) and p.R249T of the TP53 (43.87%) in D070, p.E545K of the PIK3CA (1.97%) in D453, p.R248Q of the TP53 (1.61%) in D076, and p.R273H of the TP53 (1.44%) in D372 (Table 3).