According to the bioinformatic resource CDKP, which combines and analyzes the results of genetic associations from the largest consortiums for the study of cerebrovascular diseases, risk allele A rs1136141 of HSPA8 is associated with increases in systolic blood pressure, heart rate, peripheral artery disease in ever-smokers and stroke (TOAST, other-determined) (Table 5). The gene discussed is HSPA8; the disease is peripheral arterial disease.