On the other hand, the inhibition of STAT5b in HeLa (HPV18) and CasKi (HPV16) cervical cancer cells induces a reduction in proliferation, in the colony formation capacity, in the expression of cyclin D1, and in the anti-apoptotic protein Bcl-xL, which correlates with an increase in the expression of the cell cycle regulatory protein p21, the presence of cleaved PARP, and an increase in apoptosis. This evidence concerns the gene STAT5B and cervical cancer.