Among the MMPs involved in worsening ARDS are: MMP-1 [11,62,68], MMP-2 [63,67,88], MMP-3 [10,62,65], MMP-7 [9,11,63,90,92,93], MMP-8 [91], MMP-9 [9,10,13,14,59,62,63,81,82,87,88,90,91,92,150], MMP-10 [12], MMP-12 [88], and MMP -13 [59,136]. Here, MMP12 is linked to acute respiratory distress syndrome.