Our analysis observed a huge number of lncRNAs that are capable of regulating the expression and activity of EMT transcription factors (ZEB1, Slug, Snail, Twist1) which modulate the expression of the typical EMT markers (E-cadherin, N-cadherin, and vimentin) and concomitantly induce MES transition in GBM. The gene discussed is SNAI2; the disease is glioblastoma.