The ability of OLA to reduce the expression of these pro-inflammatory markers had previously been described in in vitro studies [18,19,20,21], but this is the first time that it has been evaluated in tissues from lupus mice, suggesting that dietary OLA may decrease the presence of inflammatory infiltrates and immuno-complexes in the kidneys of lupus mice by reducing the expression of COX-2, iNOS, and mPGES-1. This evidence concerns the gene NOS2 and systemic lupus erythematosus.