The oxidative stress-related genetic variants of GPX1, GPX3, glutathione S-transferase (GST)-theta-1 (GSTT1), GST-mu1 (GSTM1), arachidonate 5-lipoxygenase (ALOX5), and cytochrome β-245 alpha chain (CYBA) have been found to influence T2DM risk [6,17,18]. The gene discussed is ALOX5; the disease is type 2 diabetes mellitus.