In addition, NSEO also affects the Th1/Th2/Th17 cytokine production by reducing the concentration of some cytokines important for regulating inflammatory processes, such as TNF and IL-10, and the Th1 response, i.e., IFN-γ, and increasing the production of IL-4 associated with the Th2 response in healthy women and HT patients. The gene discussed is TNF; the disease is hematocrit.