It has been reported that they are able to induce greater apoptosis in various cancer cells (cervical, gastric, and prostate cancers) than in normal cells, both in vitro and in vivo, by generating reactive oxygen species, suppressing angiogenesis via the Akt cell signalling pathway, and inducing apoptosis [39,40,41,42]. Here, AKT1 is linked to Familial prostate cancer.